Actinomyces Totally Explained

Everything about Actinomyces totally explained

Actinomyces is a genus of the actinobacteria class of bacteria. They are all Gram-positive and can be either anaerobic or facultatively anaerobic . Actinomyces species don't form endospores, and, while individual bacteria are rod-shaped, morphologically Actinomyces colonies form fungus-like branched networks of hyphae.
   Actinomyces are known for causing disease in humans, and for the important role they play in soil ecology. They produce a number of enzymes that help degrade organic plant material, lignin and chitin. As such, their presence is important in the formation of compost.
   Many Actinomyces species are opportunistic pathogens of humans and other mammals, particularly in the oral cavity. In rare cases, these bacteria can cause actinomycosis, a disease characterized by the formation of abscesses in the mouth, lungs, or the gastrointestinal tract.
   Some species are responsible for the smell of topsoil, which is often particularly noticeable after rain. The main chemical responsible from this smell is geosmin.

Disease

Actinomycosis is most frequently caused by Actinomyces israelii and is sometimes known as the "most misdiagnosed disease," as it's frequently confused with neoplasms. A. israelii is a normal colonizer of the vagina, colon, and mouth. Infection is established first by a breach of the mucosal barrier during various procedures (dental, GI), aspiration, or pathologies such as diverticulitis. The chronic phase of this disease is also known the "classic phase" because the acute, early phase is often missed by health care providers. This is characterized by slow contiguous growth that ignores tissue planes and forms a sinus tract that can spontaneously heal and recur, leading to a densely fibrotic lesion. This lesion is often characterized as "wooden." Sulfur granules form in a central purulence surrounded by neutrophils. This conglomeration of organisms is virtually diagnostic of Actinomyces israelii. Oral-cervicofacial disease is the most common form of actinomycosis. It is characterized by a painless "lumpy jaw." Lymphadenopathy is uncommon in this form of the disease. Another form of actinomycosis is thoracic disease, which is often misdiagnosed as a neoplasm, as it forms a mass that extends to the chest wall. It arises from aspiration of organisms from the oropharynx. Symptoms include chest pain, fever, and weight loss. Abdominal disease is another manifestation of actinomycosis. This can lead to a sinus tract that drains to the abdominal wall or the perianal area. Pelvic actinomycosis is often caused by intrauterine devices (IUD). Symptoms include fever, abdominal pain, and weight loss. Actinomyces sp. have also been shown to infect the central nervous system in a dog "without history or evidence of previous trauma or other organ involvement." (External Link

)

Treatment

Treatment for actinomycosis consists of antibiotics such as penicillin or amoxicillin for six to twelve months, as well as surgery if the disease is extensive.

Diagnosis

Consider actinomycosis when the patient has chronic progression of disease across tissue planes that's mass-like at times, sinus tract development that may heal and recur, and refractory infection after a typical course of antibiotics.

Further Information

Get more info on 'Actinomyces'.

External Link Exchanges

Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:

<a href="http://actinomyces.totallyexplained.com">Actinomyces Totally Explained</a>

Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned.